SEDDS of gliclazide: Preparation and characterization by in-vitro, ex-vivo and in-vivo techniques
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چکیده
منابع مشابه
SEDDS of gliclazide: Preparation and characterization by in-vitro, ex-vivo and in-vivo techniques.
In the study, self emulsifying drug delivery system (SEDDS) of gliclazide, a poorly soluble drug, was developed and evaluated by in-vitro, ex-vivo and in-vivo techniques. Oil and surfactant were screened out according to their solubilizing capacity. Among the tested components Transcutol HP and Tween-80 showed good solubilizing capacity. These two components were used in different ratios to pre...
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Linarin is a flavone glycoside in the plants Flos chrysanthemi indici, Buddleja officinalis, Cirsium setosum, Mentha arvensis and Buddleja davidii, and has been reported to possess analgesic, antipyretic, anti-inflammatory and neuroprotective activities. In this paper, linarin was investigated for its AChE inhibitory potential both in vitro and ex vivo. Ellman’s colorimetric method was used for...
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ژورنال
عنوان ژورنال: Saudi Pharmaceutical Journal
سال: 2014
ISSN: 1319-0164
DOI: 10.1016/j.jsps.2013.06.001